Antipsychotics

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161 Antipsychotics

The first antipsychotic, chlorpromazine, was used for the treatment of psychosis in France in 1951 and in the United States in 1954. Antipsychotic use has expanded significantly since then. The historic term neuroleptic, used with antipsychotic medication, is no longer appropriate because newer agents cause less sedation. The term antipsychotic is now preferred. In 2009, U.S. poison control cen...

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long-acting antipsychotics

long-acting (depot) anti-psychotic injection (lai) is an essential component of the treatment of schizophrenia. in this editorial, the journal tries to give a short account of the current ideas and practical aspects of lai, with respect to the iranian experience. two categories of the long-acting injections are discussed mainly regarding their dosage, intervals of their injections and availabil...

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Antipsychotics and dementia

Results Conventional antipsychotics have been widely used for BPSD; an efficacy superior to placebo was shown only at high doses, but they were associated to several and severe side effects [1]. Atypical antipsychotics showed an efficacy superior to placebo in randomized studies in BPSD treatment, with better tolerability profile vs. conventional drugs [3]. However, in 2002 trials with risperid...

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Atypical antipsychotics and parkinsonism.

BACKGROUND Atypical antipsychotic agents are thought to be less likely than older typical agents to produce parkinsonism. This has not been well documented. We compared the risk of development of incident parkinsonism among older adults dispensed atypical relative to typical antipsychotics. METHODS Retrospective cohort study of all adults 66 years and older in Ontario. We used Cox proportiona...

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TREATMENT STRATEGIES: MEDICATION Antipsychotics

standard’ treatment for treatment-resistant schizophrenia, after failure of two antipsychotics at adequate doses for an adequate duration of time. However, even after 1 year, a number of patients fail to respond to clozapine alone. We question the term ‘treatment-resistant’, which implies that little further can be done and generates therapeutic nihilism, and instead suggest the term ‘neurolept...

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ژورنال

عنوان ژورنال: Journal of Pain and Symptom Management

سال: 2011

ISSN: 0885-3924

DOI: 10.1016/j.jpainsymman.2011.03.002